"Ambry Genetics"[submitter] AND "IRF3"[gene] - ClinVar

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Items: 28

	Variation	Gene (Protein Change)	Type (Consequence)	Condition	Classification, Review status
Select item 2282851	NM_001571.6(IRF3):c.*36G>A	IRF3 (V446I)	Single nucleotide variant (missense variant +2 more)	Inborn genetic diseases	GUncertain significance
Select item 2570271	NM_001571.6(IRF3):c.*30C>G	IRF3 (P444A)	Single nucleotide variant (missense variant +2 more)	Inborn genetic diseases	GUncertain significance
Select item 2285393	NM_001571.6(IRF3):c.1276G>A (p.Glu426Lys)	IRF3 (E280K +5 more)	Single nucleotide variant (missense variant +1 more)	Inborn genetic diseases	GUncertain significance
Select item 2294670	NM_001571.6(IRF3):c.1201C>G (p.Leu401Val)	IRF3 (L255V +5 more)	Single nucleotide variant (missense variant +1 more)	Inborn genetic diseases	GUncertain significance
Select item 2606240	NM_001571.6(IRF3):c.1181A>G (p.His394Arg)	IRF3 (H359R +4 more)	Single nucleotide variant (synonymous variant +2 more)	Inborn genetic diseases	GLikely benign
Select item 2508210	NM_001571.6(IRF3):c.1145G>A (p.Gly382Glu)	IRF3 (G109E +4 more)	Single nucleotide variant (synonymous variant +2 more)	Inborn genetic diseases	GLikely benign
Select item 2306374	NM_001571.6(IRF3):c.1087G>T (p.Val363Leu)	IRF3 (V236L +5 more)	Single nucleotide variant (missense variant +1 more)	Inborn genetic diseases	GUncertain significance
Select item 2537180	NM_001571.6(IRF3):c.1063G>A (p.Asp355Asn)	IRF3 (D320N +5 more)	Single nucleotide variant (missense variant +1 more)	Inborn genetic diseases	GUncertain significance
Select item 2312540	NM_001571.6(IRF3):c.965T>C (p.Leu322Pro)	IRF3 (L176P +2 more)	Single nucleotide variant (missense variant +2 more)	Inborn genetic diseases	GUncertain significance
Select item 2337678	NM_001571.6(IRF3):c.963C>G (p.Asp321Glu)	IRF3 (D321E +2 more)	Single nucleotide variant (missense variant +2 more)	Inborn genetic diseases	GUncertain significance
Select item 2531200	NM_001571.6(IRF3):c.945G>C (p.Lys315Asn)	IRF3 (K280N +2 more)	Single nucleotide variant (missense variant +2 more)	Inborn genetic diseases	GUncertain significance
Select item 2550826	NM_001571.6(IRF3):c.915T>G (p.His305Gln)	IRF3 (H159Q +2 more)	Single nucleotide variant (missense variant +2 more)	Inborn genetic diseases	GUncertain significance
Select item 2215245	NM_001571.6(IRF3):c.781G>A (p.Val261Met)	IRF3 (V115M +2 more)	Single nucleotide variant (missense variant +2 more)	Inborn genetic diseases	GUncertain significance
Select item 2557930	NM_001571.6(IRF3):c.708G>C (p.Arg236Ser)	IRF3 (R201S +2 more)	Single nucleotide variant (missense variant +2 more)	Inborn genetic diseases	GUncertain significance
Select item 2519944	NM_001571.6(IRF3):c.694G>A (p.Glu232Lys)	IRF3 (E232K +2 more)	Single nucleotide variant (missense variant +2 more)	Inborn genetic diseases	GUncertain significance
Select item 2251993	NM_001571.6(IRF3):c.659T>C (p.Ile220Thr)	IRF3 (I220T +2 more)	Single nucleotide variant (missense variant +2 more)	Inborn genetic diseases	GUncertain significance
Select item 2361025	NM_001571.6(IRF3):c.637C>T (p.Arg213Cys)	IRF3 (R213C +2 more)	Single nucleotide variant (missense variant +2 more)	Inborn genetic diseases	GUncertain significance
Select item 2379452	NM_001571.6(IRF3):c.593C>T (p.Pro198Leu)	IRF3 (P163L +2 more)	Single nucleotide variant (missense variant +1 more)	Inborn genetic diseases	GUncertain significance
Select item 2235015	NM_001571.6(IRF3):c.565G>A (p.Glu189Lys)	IRF3 (E154K +2 more)	Single nucleotide variant (missense variant +1 more)	Inborn genetic diseases	GUncertain significance
Select item 2477978	NM_001571.6(IRF3):c.542C>T (p.Pro181Leu)	IRF3 (P181L +2 more)	Single nucleotide variant (missense variant +1 more)	Inborn genetic diseases	GUncertain significance
Select item 2606241	NM_001571.6(IRF3):c.487G>T (p.Ala163Ser)	IRF3 (A163S +2 more)	Single nucleotide variant (missense variant +1 more)	Inborn genetic diseases	GUncertain significance
Select item 2322703	NM_001571.6(IRF3):c.457C>G (p.Pro153Ala)	IRF3 (P118A +2 more)	Single nucleotide variant (missense variant +1 more)	Inborn genetic diseases	GUncertain significance
Select item 2275474	NM_001571.6(IRF3):c.451C>T (p.Pro151Ser)	IRF3 (P151S +2 more)	Single nucleotide variant (missense variant +1 more)	Inborn genetic diseases	GUncertain significance
Select item 2327291	NM_001571.6(IRF3):c.395C>G (p.Thr132Ser)	IRF3 (T132S +1 more)	Single nucleotide variant (missense variant +2 more)	Inborn genetic diseases	GUncertain significance
Select item 2602270	NM_001571.6(IRF3):c.316A>G (p.Ile106Val)	IRF3 (I106V +1 more)	Single nucleotide variant (missense variant +3 more)	Inborn genetic diseases	GLikely benign
Select item 2397052	NM_001571.6(IRF3):c.304G>A (p.Asp102Asn)	IRF3 (D102N +1 more)	Single nucleotide variant (missense variant +3 more)	Inborn genetic diseases	GUncertain significance
Select item 2251100	NM_001571.6(IRF3):c.291C>G (p.Ser97Arg)	IRF3 (S97R +1 more)	Single nucleotide variant (missense variant +3 more)	Inborn genetic diseases	GUncertain significance
Select item 2551495	NM_001571.6(IRF3):c.133G>A (p.Asp45Asn)	IRF3 (D45N)	Single nucleotide variant (missense variant +2 more)	Inborn genetic diseases	GUncertain significance

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Items: 28